Blue to the sky. Orange to the thigh.

How To Use EpiPen®

The EpiPen® Auto-Injector is a disposable, pre-filled automatic injection device that administers epinephrine in the event of a severe allergic reaction.

Remove the EpiPen® Auto-Injector from the carrier tube and follow these 2 simple steps:

Person pulling blue cap off of EpiPen device, “Blue to the sky”
  • Hold firmly with orange tip pointing downward.
  • Remove blue safety cap by pulling straight up.
    Do not bend or twist.
Person injecting orange side of EpiPen device into thigh, “Orange to the thigh”
  • Swing and push orange tip firmly into mid-outer thigh until you hear a 'click'.
  • Hold on thigh for several seconds.
EpiPen device after use

Built-in needle protection.

After injection, the orange cover automatically extends to ensure the needle is never exposed.

Call 911 after using EpiPen®.

Video : How To Use EpiPen®

Watch/listen to this video to learn how to properly use EpiPen® and how to practice with your EpiPen® Training Device. Play this video for family and friends to teach them how to use EpiPen® in the event of a severe allergic reaction.

How To Use EpiPen®
On Yourself
Screen shot of How to Use EpiPen on Yourself video

Using EpiPen® does not replace seeing a doctor or going to the hospital.

The effects of epinephrine can wear off or you could have a second reaction, so call 911, or go to the emergency room right after using EpiPen®.

If your reaction continues or your symptoms return before you receive medical attention, it’s okay to use another EpiPen® until the symptoms stop.

After getting medical help, stay close to a hospital or where you can easily call 911 for the next 48 hours.

Before leaving the hospital, remember to ask for a new prescription for multiple EpiPen® Auto-Injectors.